Reading the Whole Heart: Latent-Attention Masked Autoencoders for Multimodal Cardiac Representation Learning

arXiv:2609.12035v1 Announce Type: new
Abstract: Cardiovascular diagnosis rests on integrating complementary modalities, like ECG, echocardiography, chest radiographs, and clinical variables, each capturing distinct but correlated aspects of cardiac physiology. Yet most medical foundation models remain modality-specific, combining modalities only for finetuning or post-training. This discards the cross-modal evidence clinicians naturally integrate and ignores the structure within each modality. We introduce Latent-Attention Masked Autoencoders (LAMAE), a multimodal, structure-aware masked autoencoder that jointly learns patient-level representations during self-supervised pretraining. Rather than fusing modalities post hoc, LAMAE exchanges information directly in the latent space through a shared latent-attention module operating over a study-view-entity hierarchy, enabling aggregation of variable observations and graceful handling of missing modalities. Pretrained on over 1.2 million MIMIC-IV hospital stays, LAMAE outperforms modality-specific pretraining and strong contrastive and vision-language baselines across multimodal hospital-stay tasks, such as in-hospital mortality, ICD-10 and DRG coding, and length of stay, while remaining competitive on unimodal tasks. These gains persist even when only a single modality is available at test time, showing that modeling both intra- and inter-modal structure yields more robust, transferable representations.
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Competence-Gated Pooling of Language Models and Priors for Event Forecasting

arXiv:2609.12101v1 Announce Type: new
Abstract: In hybrid forecasting, a language model is often one of several available signals. A system may already have a market, crowd, or statistical forecast and must decide whether the model adds useful information or should be ignored. The relevant target is therefore not standalone model accuracy, but relative competence, defined as the model’s marginal value beyond the available external forecast. Under Brier loss, we characterize when model disagreement can improve an external forecast and derive the gain from using domain-specific rather than global pooling weights. We then introduce a competence gate that estimates domain-level source weights from resolved outcomes, shrinks uncertain estimates toward a global weight, and recalibrates the pooled forecast. Across 2,357 resolved binary questions and five language models, the gate improves the main external baseline from 0.0771 to 0.0732 Brier and significantly outperforms global forecast combinations. The gain remains significant under leakage controls and against a leakage-safe time-series prior on the pooled structured set, with separate evidence on FRED. In contrast, the gate gives no significant improvement on the official ForecastBench market subset, where it largely defers to the market. Across four Qwen models, verbal confidence does not reliably identify when the model outperforms the external forecast, while outcome-estimated competence supports better abstention decisions. These results provide a practical approach for selective model use based on measured marginal value.
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Language Is an Insufficient Substrate for Quantitative Reasoning, and Consequential Domains Need Large Quantitative Models

arXiv:2609.12105v1 Announce Type: new
Abstract: The prevailing assumption in applied machine learning is that progress on consequential quantitative decisions such as pricing risk, allocating capital, triaging patients, or containing a network intrusion will follow from progress in large language models (LLMs). A language model is trained on a representation of the world that was produced by human description; description is a lossy encoding of the quantitative record, and the loss is irreversible: no downstream model, at any scale, can recover from a description what the description did not encode. We formalize this as a property of the representation on which a model is trained rather than of the model capacity, and we identify three further properties that consequential settings demand of a model and that a language substrate cannot supply by construction: reproducibility, lineage from every output back to the source records that produced. it, and calibrated uncertainty. We argue that these properties define a distinct model class, which we call the Large Quantitative Model (LQM).
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Probabilistic Focal Search: Accelerating Bounded-Suboptimal Search via Lower-Bound Advancement

arXiv:2609.10584v1 Announce Type: new
Abstract: Bounded-suboptimal search seeks a solution within a factor $w$ of optimal while reducing search effort. Focal Search (FS) uses heuristic guidance within FOCAL, the frontier nodes eligible under the threshold $w f_{min}$, but its deterministic policy may leave $f_{min}$ unchanged for many expansions. We introduce Probabilistic Focal Search (PFS), which follows the FS guided choice with probability $p$ and expands a minimum-$f$ OPEN node with probability $1-p$. The latter branch encourages the lower bound to advance, enlarging FOCAL and admitting nodes that may lead to feasible solutions. By balancing guidance and lower-bound advancement, this mechanism can reduce time to a bounded solution when progress is limited by delayed FOCAL admission. As a secondary transfer experiment, we apply the same scheduler to Dynamic Potential Search, yielding Probabilistic Dynamic Potential Search (PDPS). We benchmark PFS against FS on N-Puzzle, Pancake Sorting, and the Traveling Salesperson Problem (TSP), and evaluate its anytime extension on the Generalized Covering TSP (GCTSP), using multiple $w$ and $p$ values. Across these benchmarks, the largest gains occur when long $f_{min}$ plateaus delay useful FOCAL admissions; in such settings, the probabilistic factor may reduce node expansions by about 90% or more (e.g., on N-Puzzle and TSP). For the anytime algorithm family, Anytime Probabilistic Focal Search (APFS) outperforms all tested algorithms in evaluating anytime methods on GCTSP. We also observe that the benefit is smaller when the deterministic search already advances efficiently (e.g., Pancake Sorting), indicating that the probabilistic factor is most useful when FOCAL admission is a search bottleneck. The PDPS transfer shows that the mechanism also transfers to potential guidance, although its common-success effects remain domain- and bound-dependent.
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Automating Quadratic Unconstrained Binary Optimization (QUBO) Formulation Generation from Natural Language

arXiv:2609.10629v1 Announce Type: new
Abstract: Quadratic Unconstrained Binary Optimization (QUBO) is a central formulation for combinatorial optimization and has gained increasing attention due to its compatibility with quantum, hybrid quantum-classical, and quantum-inspired solvers. However, translating natural-language problem descriptions into correct QUBO formulations remains difficult, requiring the identification of binary variables, constraints, objective functions, penalty terms, and suitable penalty weights. This process is time-consuming and often demands substantial domain expertise. To address this challenge, we propose an end-to-end multi-agent framework that automatically generates QUBO formulations from natural-language problem descriptions, supported by structured or unstructured test cases. To evaluate its performance, We also introduce QUBOBench, a benchmark containing 100 combinatorial optimization problems across 12 application domains, curated from peer-reviewed literature, competitions, and canonical NP-hard problems. Experimental results show that our framework achieves 68% accuracy on QUBOBench, outperforming a direct single-call baseline by 22%. Further analysis identifies iterative self-repair as the most important component contributing to improved performance. The data and code are open-sourced at https://quitttcat.github.io/QuantumQUBOAgent.
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A Multi-Stage Rule-Chaining Framework for Compositional and Interpretable Cognitive Reasoning

arXiv:2609.10654v1 Announce Type: new
Abstract: The Abstraction and Reasoning Corpus (ARC) benchmarks cognitive generalization, the ability to infer and apply abstract rules from limited examples. This paper presents a multi-stage rule-chaining framework that performs compositional reasoning across symbolic, structural, and conceptual levels. The framework integrates three complementary solvers:
(1) a deterministic rule discovery module that induces atomic transformations through geometric, color, and object-based analysis;
(2) a pattern-composition engine that reconstructs outputs via block merging, repetition, and spatial heuristics; and
(3) a structural abstraction layer that infers hierarchical and nested relationships across grids.
These solvers operate sequentially within a progressive fallback hierarchy, where each stage reuses prior reasoning traces to enhance interpretability and generalization. Training passed for 995 tasks out of 1000, further evaluated on 105 tasks out of 120 and solved 230 test tasks out of 240 ARC-AGI-2 tasks. The system achieved strong coverage across deterministic, compositional, and abstract categories, demonstrating an overall accuracy exceeding 95 percent. The proposed architecture bridges symbolic reasoning and pattern synthesis, providing interpretable insight into cognitive generalization. The results suggest that rule chaining and hierarchical composition can advance machine reasoning toward transparent, human-aligned abstraction without relying on task-specific tuning.
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